Jake Sully – imdb.com profile
Sigourney Weaver – Dr. Grace Augustine – imdb.com profile
Michelle Rodriguez – Trudy Chacon – imdb.com profile
Zoe Saldana – Neytiri – imdb.com profile
Giovanni Ribisi – Selfridge – imdb.com profile
Stephen Lang – Col. Quaritch – imdb.com profile
Laz Alonso – Tsu’Tey – imdb.com profile
Wes Studi - imdb.com profile
Joel Moore – Norm Spellman – imdb.com profile
CCH Pounder – Moha – imdb.com profile
Peter Mensah – Akwey
Julene Renee – Med Tech #1
Matt Gerald – Lyle Wainfleet
Peter Dillon – Shuttle Crew Chief
Sean Anthony Moran – Fike
Kevin Dorman – Tractor operator
Dean Knowsley – Pilot
Dileep Rao – Dr. Max Patel
Noli McCool - Diui
Nick Miller – Airfield Trooper (uncredited)
Logan Pithyou – Blast Technician (uncredited)
Grant Roa – Bouncer (uncredited)
Woody Schultz – Med Tech #2 (uncredited)